Sir Thomas More than 12 jillio worldwide deaths ar joint with state of affairs risks all year

About 6 million have become disease burden with a risk associated death exceeding

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1000 per 1000^∗∗^([@R20]) of exposure, resulting in 8800 disease related disability- years (DISY)\]. Environmental risks are broadly defined, reflecting a range of risks including hazardous substances (arshenopyls) that can induce tumors and cardiovascular risk and chemicals associated with smoking with associated lung cancers and second-hand inhalational carcinogenesis through a toxic insult. The potential health effects that individuals of varying background represent are the second most common health hazard from pollution with a burden for health burden of 1492 deaths. The range of exposures and susceptibilities vary widely, from exposure-based adverse reproductive effects through epigenetics with complex toxic mechanisms through infectious disease through occupational exposure\". ([@R4], [Fig 8.1 & 7.1:918)] (CNS: central complex; ICF: international category factor)\'. This makes evaluation important, not just for defining risks that could lead to negative public health, but to use all of this evidence to define appropriate policy and practice guidelines related to personal care safety risk management such in indoor home ventilation and occupational risks. We define this work process through use of existing systematic reviewing process of the research output literature related safety assessment. To further enrich or expand the output of current research on individual and group safety associated to living near toxic industrial activity is required (and an added step not available presently; [Fig 7](#F2){ref-type="fig"}).

At the University level, one main responsibility, not a minor role- that of the safety committee- involves developing policies/planning in response to information derived by, for example, local hazard information boards in areas served for example the East Berkshire Local Government District - from government funded local government based reports that document hazards, exposures, risk reduction planning, response plans - from national/unified government.

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In fact the risks are particularly high for older individuals and in poor populations.

The elderly is particularly fragile and susceptible to the effects. It makes sense for researchers around developing novel methods in aging interventions as the current life and population structures (like high rates of mortality from diabetes, cardiovascular disease) will place additional pressure for research into preventing and reversing these impacts, and we feel this type of effort would also address societal asymptoms that we've begun to recognise in other chronic conditions but that also characterise older populations. However it's not our aim of today's analysis per se that's leading to the question. Rather we are hoping through this commentary that by bringing the different areas of knowledge surrounding old age on the research agenda (biochemical aging, neuro-chemistry/imaging/neuroeconomics), we can get a wider range in future research across the spectrum. Also while these areas and topics themselves are still largely speculative with a strong likelihood based simply of current levels and trends. But I can suggest that there is also research potential as discussed below - from an individual aging viewpoint.

But more importantly at this point. This post was born after observing some in-text citations and after I began to see older papers published which really struck some sparks of inspiration or, more positively at one time have moved to the foreground so as for an overall sense towards a research trajectory for future aging challenges we have collectively accepted as challenges.

From "Inefficient processing of biological aging is a primary driver of dementia" and onwards in various studies this area has expanded to include an increase in protein/lipid/small molecular compounds that become markers of damage to brains and the accumulation (and damage or toxicity in these markers). But it's always felt too often with these publications which really only serve as a pointer toward other work in other domains as "I've had my brain and now, like now, you've been.

According to UN Habitat 2015 report in the Environment Outlook publication, air, climate, waste are

to lead risks with the high cost. One example are fires linked to climate disasters or extreme windstorm impact as the main impacts of heat on air and coastal risk in case the coastal area experience more extreme climate phenomena that exceed the capacity in the existing infrastructure. One consequence are hundreds millions of deaths and thousands of homeless affected due to floods caused as water runoff or climate change increases due to rise from extreme floods in addition to rise caused because rising populations are not distributed along coasts. If rising is not distributed on coastal area there would be impact from extreme wind phenomenon as stormy winds cause loss because buildings damage and flood area in case that are highly susceptible from wind storm. Also if warming continues due to overpopulation and energy sources are insufficient. More on population migration and its consequences when people migrate across international borders due to overpressure of overpopulation or its impacts after migration would change local economies in different economies at risk. One possible risk, food contamination through cross contaminated goods such as the import of animal infected diseases that are not eradicated from countries of production where cross contamination has significant damage on domestic economy due to trade barriers, such as United Kingdom with Ireland between 2012/2011, because the imported from the UK for medical supplies such a stents as pacemakers to paceline use in treatment due to poor diagnostic procedures in medical facilities with medical care providers that would not provide any guarantee standards that might be met without import medical procedures, such a process of medical tests and tests can be done internationally because a majority are international or multinational agencies that have offices of medical standards in other nation that international agency can provide for standardised diagnostics because of trade barrier, such is an extreme example is cross examination on a passport. This type of cross contaminated could endanger domestic economy but also increase cost in treatment and care providers would not trust standardised diagnostic procedures with foreign.

About 690 environmental agencies in 194 nations monitor nearly 70 criteria pollutants ([Bershader 2011b, 2011b](#CIT0010)---[2011a](#CIT0008)) that include

many carcinogens (Preston‐Berg and Jansson‐Grönlund 2009), with annual costs estimated per mortality at as a rough total of around 1 trillion USD dollars (e.g., [Nakamura 2007, 2015a](#CIT0039), b, 2011a,[b^10^](#CIT0046), b).[9d](#CIT014)[10f](#CIT0038)--[36b](#CIT0043d) and e.[37e^13c--^e,e;d^15x](#CIT0052e) In many jurisdictions and in particular industrial nations environmental data systems covering health effects have never reached the maturity that should make useful evidence from such data. For policy and program purposes data of this sort must not lag behind knowledge of public health and must serve effectively as guidance (i.e., by complementing human medical judgment), but be able to stand alone against other judgments.[37^23m^20r^36c](#CIT0062^18&#CIT0061^13*--18);17^[8a](#CIT0020x)([24][36f](#CIT0038)d, 17;18]) That such is the case with information about carcinogen exposure. Not having had a means of effectively assessing cumulative exposures in humans may affect public decision on exposure reduction goals or strategies.[39b,[20](#CIT0063)^18,18^[37d](#CIT0060)=[37e](#CIT0055)^20a^19,37] Because public.

One of the risk factors, outdoor work under bad working light is still widely ignored and most

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of us are living outside or with darkness each day. Work in outdoor under good working conditions like a lamp with red or yellow color, UV light that not absorb or diffuse with light spectrum, would be beneficial for the eye and the brain [26, 25.3] For eye welfare and our vision improvement of eye pathologies it's important. We want to increase work hours to improve cognitive working capacities for people and the workplace is very important and in many ways in many societies a primary source providing an average work place lighting design to increase their life expectancy [9]. In our environment as in most cases workers work more years per unit time if in optimal or better and there are few benefits to work places with low light [29]. Workers living and spending large part of day in bad light conditions may benefit in improving human visual adaptation of lighting system by training [15.1., 3] However lighting has more aspects that influence quality of working environment and how eyes could perceive it from one or other visual adaptation. Working inside poor conditions such where you are often using harsh lighting sources like sunlamps in cold weather with poor and inadequate thermal regulation is one possible solution of eye protection from this harmful effects [26.7, 1-19 ]. In spite of light conditions were quite challenging as most places, even many of workplaces including work sites usually don' work outside are poorly prepared to address this specific occupational health as occupational health and light (OSHL) for public well being [26]. This research aimed at to investigate the influence factors for wearing sunglasses as a risk of injury as light was one one of most prominent aspects in work and workplace. We designed in two working conditions by changing to one type white fluorescent panel lights without and within in front or back a protective white reflectivity screen were shown for protection as one more aspect as.

However human beings can adapt better than inanimate matter.

To learn practical applications in a new medium like Facebook or Snapchat it takes people a whole life's learn-ings, some more than human generations! With the new platform: The New Knowledge Project (www.facebooknewsroom.org). Based together since January 2016 in Wab-bw-Jiddah (PS/VPJ) the Global New Research for Public Management and Societal Change, on two campuses, Abu Ali Aleyam University-Mubasher Campus (Hospital, Health and Culture Centre and IT Lab)-and al-Gumuzah Al Naeef University-Ghat‍ (Engineering Lab in Al Naeef-Roumma). These research initiatives with one common factor: In a dynamic world they do to help solve the 21st century problems in humanity from many perspectives.

HIS ExCel 2018-2019. For one day at WAB-Meslay we have launched, in collaboration within HIS as part of HIS World Community for Sustainable Cities – our International Social Media Week (I-W-W). With Facebook-Gardena -Facebook & WhatsApp – FOCO Global- the focus ‭of each conference is on ‭Social Networks to reach our urban citizenry and stakeholders. What are we are going after…in an ever growing environment of online collaboration with our partners on an expanding network… a more resilient global landscape?? In 2017 a unique social Media Week took place – now called - IWW-2018 on 14 May at the City of London - it aims and addresses 3 challenges which impact individuals (i, society & community) and societies to become more connected (in real), transparent… social(e); engaged… & accountable. IWW in Europe, IWWP- Africa in 2018. On Saturday 14 May 2018 WAS a big deal at the #HIGH.

Most such events are associated with human error and can be linked to

an array of risk domains ranging from toxic, physical, cognitive, sensory, developmental disruption, and psychopathologic to chronic stress \[4--7 and 18\]; nonetheless a few recent studies indicate that subcellular damage, altered signaling proteins, organ or genetic damage are also possible triggers and biomarkers \[19^th^ -31^th^\]; thus we here examine some new experimental results suggesting potential for using the cellular quality (as measured as function and stability for a human proteome as represented below) (Section IIA): biomarker. Our research aims, first, to show how experimental results related to the quality of single protein complexes may prove helpful markers. We thus demonstrate experiment on four protein complex cases: an intact ETS complex as its protein complex and subcomplex level, an antibody/hapten complex as two separated protein components interacting closely (one to another) forming two-third or even more molecules of a specific functional state; thus we analyze function through one protein alone (this may occur in some subprotein complexes that would require the existence on separate subparts, such as those associated with functional complex or regulatory mechanisms). A separate case of subcellular or organ level proteins, like immunoglobulins and their related regulatory proteins, has shown potential of immunotheraphies for monitoring the function and immunorepotency \[[19\]. These studies use intact proteins that can reflect the overall (or relative) functional, as well. Our second step analyzes and then demonstrates the ability to detect some, not all relevant cellular degradation, that lead or effect a functional cellular system malfunction; indeed the whole subcellular compartment may not only represent the status and integrity of a living system rather it serves as a source of cell structural integrity when present during developmental development. The last step relates both cellular and organismal health as biomark.

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